Use of Imodium in Kids

Use of Imodium in Kids (UIC) is a medication used to treat diarrhea caused by many types of infections. Its main use is to prevent dehydration and other complications from diarrhea. However, it may also be used when other treatments have failed or are not effective enough. UIC was approved for treatment of acute diarrhea in adults and children with severe cases of Clostridium difficile infection (CDI). It is also used to treat patients with chronic diarrhea due to C. difficile infection. UIC has been shown to reduce symptoms of CDI in children and adults, but its effectiveness in treating these conditions is still being studied.[1]

The drug works by inhibiting the growth of bacteria that cause diarrhea and reducing their acidity. When ingested, it causes nausea and vomiting which helps relieve pain associated with diarrhea. Because it is taken orally, it does not cause stomach upset. UIC is usually given once daily. It should be administered within 4 hours after the onset of diarrhea or up to 48 hours after the last episode of diarrhea.[2][3]

Side effects include: nausea, vomiting, abdominal cramps, constipation and headache.[4]

Loperamide Dosing for Pediatric Patients [ edit ]

In general pediatric patients require higher doses than adult patients. According to UpToDate, the recommended dose for an adult is 2 mg/kg as a single dose. For children under 12 years of age the dose is 0.5 mg/kg as a single dose. The medication should be taken with plenty of fluids and may be repeated in one hour if necessary.

Patients should be reassessed periodically to determine if treatment should be continued or not.

Side effects are mainly centered around watery diarrhea and abdominal cramping. Rarely, tachycardia or anaphylaxis may occur.

Loperamide Syrup for Infants and Children [ edit ]

Loperamide syrup is available over the counter (OTC) for children over two years of age, but it is important to remember that its use in children under 2 years of age has been associated with rare, but serious cardiac effects. It is also recommended to seek medical attention if the child has a history of Long QT syndrome, or is taking drugs that are known to prolong the QT interval. Additionally, children who have problems with constipation should not use this medication.

Onset of action for loperamide is usually within one hour, but can be up to three hours. For this reason you should reassess your patient after one hour.

Dosage for children under 2 years: 0.1 mg/kg (maximum dose: 4mg)

Dosage for children 2 to 11 years: 0.2mg/kg (maximum dose: 8mg)

Adverse Reactions [ edit ]

Abdominal discomfort, diarrhea, headache, nausea, vomiting, abdominal pain.

Sources & references used in this article:

IMODIUM by A Thermometer – CAN. FAM. PHYSICIAN, 1983 –

IMODIUM by WP Pain, MS Quit – world, 1976 –

Secondary anorectal surgery for the missed puborectalis muscle by WB Kiesewetter, MR Jefferies – Journal of Pediatric Surgery, 1981 – Elsevier

Motivations for Diverted Buprenorphine Use in a Multisite Qualitative Study by PR Kavanaugh, K McLean – Journal of Drug Issues, 2020 –

West Nile Incidence on the Rise, CDC Reports by RS JEFFERSON – Pediatric News, 2006 – …