Tramadol is a medication which was developed in Germany in the early 1970’s. It was originally designed to treat pain associated with cancer chemotherapy. Since then it has been approved for various other conditions such as chronic pain, depression, anxiety disorders, and insomnia. However, it is most commonly prescribed off label (used outside its original intended use) for treating moderate to severe pain from injuries or surgery.
The drug is available in several strengths ranging from 25 mg to 200 mg. There are two main types of tramadol: extended release tablets and immediate release capsules. Extended release tablets contain 50% more active ingredient than regular tablets, while immediate release capsules contain 75% less active ingredient than regular capsules.
Tramadol has been shown to have analgesic properties similar to morphine but without the risk of addiction. Its mechanism of action involves blocking the reuptake of noradrenaline, serotonin, and dopamine. These neurotransmitters are responsible for many physiological functions including mood regulation, appetite control, sleepiness/insomnia, nausea and vomiting, cardiovascular function and pain perception.
Side Effects of Tramadol
There are no known significant adverse effects associated with tramadol at any dose level. There are also no serious adverse effects known at this time. In fact, the most common side effect reported with tramadol is mild nausea, which should subside in a day or two.
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