Tocopheryl Acetate: Does It Really Work

Tocopherol (vitamin E) is a powerful antioxidant that protects against free radical damage. Free radicals are unstable molecules made up of oxygen and hydrogen atoms. These unstable molecules can cause cell damage, such as DNA mutations, cell death or even cancer. They may also react with other substances in your body, causing inflammation and pain. Vitamin E helps prevent these harmful effects caused by free radicals.

Free radicals are created when certain foods and chemicals in our environment interact with each other. Some examples include cigarette smoke, air pollution from factories, ultraviolet light from sunburned skin, tobacco smoke and alcohol consumption.

Vitamin E is found naturally in many fruits and vegetables. It is also available as a dietary supplement.

The most common form of vitamin E is called alpha-tocopherol (α-TOH-poh-ROL). Other forms of vitamin E have been synthesized, but they are not as effective at preventing oxidative stress. α-TOH-poh-ROL is the only form that is considered safe for human use.

In addition to its antioxidant properties, α-TOH-poh-ROL has antiinflammatory and immune system boosting qualities.

Vitamin E is known to reduce the frequency and severity of asthma attacks in children (and adults). It does this by improving lung function and decreasing inflammation. People who take Vitamin E may experience fewer respiratory complications and shorter recovery time after an asthma attack. In some cases, it may even prevent asthma attacks from happening altogether.

A vaccine developed at the University of Virginia used α-TOH-poh-ROL to treat asthma in mice. Mice who received the treatment had less lung inflammation and buildup of mucus. They also experienced a decrease in other asthma symptoms such as wheezing and shortness of breath.

Vitamin E may help prevent heart disease by reducing blood vessel damage. It may also lower high blood pressure and cholesterol levels.

Vitamin E has been linked to a decreased risk of certain cancers, including prostate and gastric cancer.

It is believed that the antioxidant properties of Vitamin E may help prevent certain conditions of the eye, such as macular degeneration and cataracts.

There is some evidence that taking a combination of antioxidants (including Vitamin E) may improve fertility in women with infertility issues. More studies are needed to confirm these findings.

Vitamin E has been used to slow the progression of neurological diseases such as Alzheimer’s disease.

The therapeutic dosage of α-TOH-poh-ROL is up to 1000mg per day, and can be increased to 1500mg per day if the person is under a lot of oxidative stress.

There is no known danger to consuming high dosages of this form of Vitamin E, however it may cause nausea when first taken.

Vitamin E has been used with a great deal of success in the treatment of many conditions. It is an important antioxidant that helps prevent oxidative stress-related conditions.

Vitamin E is a fat-soluble vitamin found in many foods. It’s also available as dietary supplements.

Vitamin E is a powerful antioxidant that helps prevent free radical damage to cells. It is used to prevent conditions such as heart disease and cancer.

Some studies have indicated that Vitamin E may also be useful in the treatment of asthma and other respiratory conditions.

α-Tocopherol acetate (α-TOH-poh-ROL ah-seet) is the synthetic form of Vitamin E used in asthma treatments.

Vitamin E is a fat-soluble antioxidant that helps protect cells from damage caused by free radicals. It is found in many foods such as nuts, seeds, vegetables oils, and wheat germ oil.

Vitamin E is also available as a dietary supplement, typically as dl-α-tocopherol (dl-α-TOH-poh-ROL). Both the D and L forms of tocopherol are nutritional supplements.

Vitamin E is used for a wide variety of things, some of which are supported by scientific evidence while others are not:

Treating or preventing Alzheimer’s disease

Treating or preventing heart disease

Lowering cholesterol levels

Preventing eye diseases, such as macular degeneration and cataracts

Treating lung conditions, such as asthma and chronic bronchitis

Treating male infertility

Treating female infertility

Treating complications during pregnancy

Treating blocked arteries in the legs (peripheral artery disease)

Treating foot pain caused by poor blood flow (diabetic neuropathy)

Treating tingling or numbness caused by poor blood flow (peripheral neuropathy)

Vitamin E is considered a “reputed anti-aging supplement” taken by mouth for such things as improving memory, reducing mental decline, and improving immune system functioning.

Bodybuilders and athletes sometimes take vitamin E supplements because it is believed to reduce muscle damage during workouts.

Vitamin E is also used as a mouthwash to reduce swelling (inflammation) of the mucous membranes in the mouth (stomatitis), and at times to treat acne or dandruff.

Most uses of Vitamin E are for conditions that are related to old age or exposure to oxygen and other substances (free radicals).

There is some scientific evidence that taking Vitamin E by mouth might prevent coronary heart disease and colon cancer.

However, it is not clear if Vitamin E supplementation can prevent these conditions, or if the results of studies showing this effect were due to an unrelated factor.

Vitamin E has been used with mixed results to treat asthma, but it has not proven useful for treating coronary artery disease or strokes.

Although some evidence suggests that taking Vitamin E by mouth might slow the decline of mental function in older people, other evidence suggests that Vitamin E supplementation does not prevent Alzheimer’s disease or Parkinson’s disease.

Vitamin E supplementation also has not been proven to prevent hearing loss or age-related macular degeneration.

Vitamin E has not been proven to be effective when applied to the skin for conditions like eczema or psoriasis.

Infants who are fed only mother’s milk, and not other foods, are deficient in Vitamin E and might experience problems with their immune system, intestinal tract, and nervous system if not supplemented.

About 60% of adults do not get enough vitamin E from their diet.

While there is no RDA (Recommended Dietary Allowance) for vitamin E, most experts agree that adults need at least 10mg a day and can safely take a maximum of 1,000mg a day.

Vitamin E is safe for most people when taken in appropriate amounts.

Taking higher than the recommended amount (1,000mg) of Vitamin E daily might increase the risk of bleeding and stroke in some people.

Vitamin E is likely safe when taken by mouth short-term or for a few years.

Due to a lack of studies using Vitamin E long-term, its safety for use over several years is not known.

Some doctors believe that because vitamin E acts as an antioxidant, it might help prevent certain kinds of cancer.

Research, however, has been inconclusive.

Taking large amounts of vitamin E (more than 400 IU) might increase the risk of death in some persons, especially those who have cancer or heart disease.

There is also some concern that using vitamin E to prevent cardiovascular disease is harmful and might worsen the condition.

The U.S. Food and Drug Administration (FDA) recommends that people only take vitamin E supplements under the supervision of a healthcare professional.

Vitamin E is a term used for a set of eight related compounds, four tocopherols and four tocotrienols.

All these are members of the group of chemicals known as antioxidants.

Vitamin E was first recognized as an essential nutrient in 1922.

The first evidence that it is a powerful antioxidant came from laboratory experiments in 1922.

In these experiments, rats whose food was enriched with vitamin E lived longer than expected when exposed to toxins that normally produce lung damage.

Vitamin E is found in a wide range of foods, including vegetable oils, margarines, and nuts.

Good sources include sunflower seeds, pumpkin seeds, almonds, pecans, and spinach.

Vitamin E is not stored in the body, so it must be consumed daily.

Deficiency is rare due to the fact that it is found in many foods.

Vitamin E is lipid soluble, which means it is absorbed along with dietary lipids (fats).

Nearly all of the vitamin E in the body is found in cell membranes, especially in the walls of blood vessels.

Vitamin E helps prevent the buildup of fatty deposits in arteries and veins.

It keeps the walls of the veins and arteries supple and prevents them from hardening.

Sources & references used in this article:

Calorimetric and infrared spectroscopic studies of the interaction of α‐tocopherol and α‐tocopheryl acetate with phospholipid vesicles by J VILLALAIN, FJ ARANDA… – European journal of …, 1986 – Wiley Online Library

The distribution and relative hydrolysis of tocopheryl acetate in the different matrices coexisting in the lumen of the small intestine during digestion could explain its low … by C Desmarchelier, F Tourniaire… – Molecular nutrition & …, 2013 – Wiley Online Library

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High doses of vitamin E in the treatment of disorders of the central nervous system in the aged by GT Vatassery, T Bauer, M Dysken – The American journal of …, 1999 – academic.oup.com

Alpha-tocopherol content of foods by RH Bunnell, J Keating, A Quaresimo… – The American Journal …, 1965 – academic.oup.com

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The effects of vitamin E and training on physiological function and athletic performance in adolescent swimmers by IM Sharman, MG Down, RN Sen – British Journal of Nutrition, 1971 – cambridge.org

Pediasure–Is this Really What Kids Need to Grow? by M Daly – 2014 – wellnessplus.net

Thirteen-week toxicity study of d-α-tocopheryl acetate (vitamin E) in Fischer 344 rats by KM Abdo, G Rao, CA Montgomery, M Dinowitz… – Food and Chemical …, 1986 – Elsevier