SGOT Blood Test: Normal Range?
The SGOT blood test measures the amount of hemoglobin (Hb) in your red cells. Hemoglobin is a protein that carries oxygen from the lungs to all parts of our body. When there are too few or not enough oxygen molecules available to different organs, it causes diseases such as anemia, fatigue, weakness and even death. The SGOT test is used to determine if the Hb levels are within the normal range.
There are two types of SGOT tests: A and B. Both types measure the same thing but they do so in slightly different ways.
A Type 1 test measures Hb at four locations on your body, including your spleen and liver. These sites are called “sites I” through “site 4.” Sites I and II measure the most Hb because these are where the majority of red blood cells originate from.
If you have less than 150/µl of Hb at site IV, then you probably don’t meet the criteria for being in good health.
Site III measures only a small amount of Hb. Site III is located between sites I and II near your heart and lungs.
You may need to take additional steps to improve your overall health before taking this test. If you have Hb levels less than 100/µl at site III, then you probably don’t meet the criteria for being in good health.
A Type 2 test measures only Hb at the spleen, which is considered to be the most accurate way to test. Your spleen manufactures new red blood cells, so if your body can’t produce enough of them or the quality of them is too poor, it will be reflected by your spleen.
Men and women are considered not in good health if they have less than 150/µl of Hb at the spleen.
The lab report will also indicate two other things: First, a general idea about how much Hb you have overall. If you have more than 12.5/µl of Hb then you are in good health.
Second, the lab report will state whether any of your organs are not functioning properly.
What is the Meaning of sgot Test?
The SGOT test is a blood test that checks the level of an enzyme called “alanine aminotransferase”, which is often referred to as “ALT” for short. Enzymes are specialized proteins that help speed up chemical reactions. The ALT enzyme is found in high concentration in the liver. The SGOT test can help detect liver disease and other conditions, such as hepatitis and pancreatitis.
The SGOT test is sometimes called the “serum glutamate oxaloacetate transaminase” or SGPT. These names are outdated, however, and most medical professionals just refer to it as the “ALT” test.
What does sgot Test?
The ALT enzyme helps break down protein in the liver. If the liver is damaged, then it releases its stored proteins into the blood. One of these proteins is called “alanine,” and it is the building block for another chemical called “glutamate.” The ALT enzyme breaks down the alanine into glutamate.
The SGOT test measures the amount of glutamate in the blood. As the liver gets healthier, the more glutamate gets converted back to alanine.
However, if there is too much damage, then there ends up being more glutamate in the blood and less alanine. This shows up as a higher SGOT level.
A high sgot test is usually a sign of liver disease. However, other conditions can also increase the SGOT level.
These include hepatitis, heart failure and even certain medications. Caffeine and alcohol can also temporarily increase the level.
How is sgot Test Done?
The doctor will prick your finger and collect several drops of blood in a vial or tube. He will then send the vial or tube to a medical laboratory for analysis. Usually, the lab technicians will check the SGOT level right away. It takes several days to get the final results back from the lab.
Sometimes, the lab technicians will need to analyze the blood sample with more specialized equipment. This might involve separating the serum from the rest of the blood sample.
They can then analyze the SGOT level directly from the serum. It may take several days to get the final results back.
How is sgot Test Diagnosed?
The test is usually done when a patient displays liver problems or symptoms of liver disease. It can also be used to monitor the effectiveness of medication or treatments for liver disease. The results are generally not available for a few days.
What Affects sgot Test?
Sometimes, it takes time for the liver to regenerate after an injury. In such cases, the SGOT level will continue to rise for up to three months after the initial damage occurs. This is why it’s important to get regular check-ups if you suffer from liver problems.
What Are sgot Test Results?
A perfectly normal result is a level between 7 and 40 U/L. Higher than 40 U/L is a sign of liver disease and levels above 67 U/L usually indicate possible liver failure.
The test results will also determine what treatment you receive. For example, if the test shows a higher than normal level, your doctor may order a second test to confirm the results.
If your levels are close to the high end of normal, the doctor may just ask you to return in a few months for another check-up. On the other hand, if your levels are at the low end of normal, the doctor may just ask you to return in a year.
How Should sgot Test Results Be Used?
The sgot test can show if you have liver damage or not. This can help save your life if it detects liver disease early enough. Many people with liver disease do not experience any symptoms until the disease is in an advanced stage. It is very important to get regular check-ups if you have existing liver disease or a risk factor for the condition.
The sgot test can also help determine how well your treatment for liver disease is working.
Last but not least, the sgot test can help determine if you need to avoid certain drugs and medications. Some of these drugs can place an additional strain on your liver or even damage it further.
Your doctor will be able to provide a complete list of these drugs after examining your test results.
Do I Need sgot Test?
The sgot test is not mandatory and you do not need to get it done for any reason. It can, however, help save your life by detecting liver damage before it becomes too late.
You should get the sgot test if you experience any of the risk factors for liver disease listed above.
Sources & references used in this article:
The clinical significance of the SGOT test. by RR Babb – California medicine, 1973 – ncbi.nlm.nih.gov
The SGOT/SGPT ratio—an indicator of alcoholic liver disease by JA Cohen, MM Kaplan – Digestive diseases and sciences, 1979 – Springer
Hospital admission laboratory profile interpretation: the SGOT and SLDH-SGOT ratio used in the diagnosis of hepatic disease by GW Cole, W Bradley – Human pathology, 1973 – Elsevier
Aminopyrine N-demethylation: a prognostic test of liver function in patients with alcoholic liver disease by JF Schneider, AL Baker, NW Haines, G Hatfield… – Gastroenterology, 1980 – Elsevier
Pulse analysis as a possible real-time biomarker complementary to SGPT and SGOT for monitoring acute hepatotoxicity by TL Hsu, Y Chiang, WK Wang, PT Chao… – Toxicology …, 2003 – Taylor & Francis