Quinapril, Oral Tablet

Quinapril Brand Name (Generic)

The brand name of Quinapril is Quillivant XR. The generic version of this drug is called Qsymia. You may have heard the word “Qsymia” used before, but it was not always clear what exactly it meant. Now that you know its meaning, you will be able to better understand how the brand name is different from other drugs like it.

What Is Quinapril?

Quinapril is a prescription medication that treats some types of high blood pressure. Quinapril works by lowering your blood pressure. This medicine is available only through a doctor’s prescription. It is effective in treating hypertension, which occurs when the amount of fluid in your body increases too much due to stress or illness. Some common side effects include: dizziness, nausea, vomiting and diarrhea.

How Does Quinapril Work?

Quinapril lowers your blood pressure because it reduces the amount of salt in your blood. Salt is necessary for maintaining proper levels of water in your cells and keeping them healthy. When salt concentration drops, so does the level of fluid in your body. This causes a drop in blood pressure, which means less pressure inside your arteries and veins. Your heart rate slows down as well since there are fewer blood vessels pumping faster than normal.

Quinapril is a water pill, also known as an anti-hypertensive. This drug lowers blood pressure by blocking the actions of chemicals that tighten blood vessel walls. By lowering your blood pressure, quinapril relieves stress on the heart and improves circulation, which in turn lowers the strain on the heart while increasing oxygen supply throughout your body.

Quinapril is able to lower your blood pressure by blocking the actions of chemicals that tighten blood vessel walls. It is also able to stop the activity of certain enzymes within the heart and blood vessels that affect blood pressure.

Quinapril is specifically used to treat mild, moderate or severe high blood pressure. It is also used to prevent strokes in patients with high blood pressure and coronary artery disease; to improve survival after a heart attack; and to improve survival after surgery to open up a narrowing or blockage in a heart artery.

Quinapril is an angiotensin-converting enzyme (ACE) inhibitor. It works by relaxing blood vessels and lowering blood pressure.

Quinapril is used to treat high blood pressure (hypertension), and to help prevent organ damage in people with congestive heart failure, diabetes, or renal disease. It is also used to improve survival after a heart attack.

Quinapril may also be used for purposes not listed in this medication guide.

What Are the Important Safety Information for Quinapril?

Quinapril can cause severe allergic reactions. Symptoms include swelling of the face, lips, mouth, or tongue that impedes breathing or hives. Get immediate medical attention if you have these symptoms.

Quinapril may increase the risk of coronary artery disease (hardening of the arteries). This risk is further increased if you smoke or have high LDL cholesterol, high triglycerides, or if you are postmenopausal and not taking estrogen. Talk to your doctor about whether you should take a non-steroidal anti-inflammatory drug or a lipid-lowering medicine.

Quinapril may cause an adrenal gland disorder. Tell your doctor if you have very low levels of cortisol, if you stop having periods, or if you become very tired even after sleeping a long time.

Quinapril may make it harder to tell when you have the signs of low blood sugar. Always carry a source of sugar with you in case of an emergency.

Quinapril may cause serious effects on the fetus developing in a pregnant woman. See the doctor immediately if you are pregnant and have been using this medicine.

Quinapril may cause eye problems, including the growth of increased pressure in your eyes. Your doctor will periodically check for this during your use of quinapril.

Quinapril may increase the amount of potassium in your blood. Your doctor may prescribe a medication to help prevent this problem, or may monitor you more closely if you are also taking a potassium supplement.

Do not use salt substitutes that contain potassium.

Quinapril may cause swelling of the tongue or floor of your mouth. Use caution when drinking liquids or smoking. If this problem does occur, you will need medical attention.

Quinapril may cause dizziness, light-headedness, fainting, or vision problems. Do not drive or operate heavy machinery until you know how this medicine affects you.

Quinapril may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking this medicine.

Long-term use of quinapril may increase the risk of heart failure. Your doctor may want to monitor you for this, especially if you are elderly.

Quinapril may cause you to become dehydrated, resulting in a drop in blood pressure. Be sure to drink enough fluids during hot weather and during exercise.

Talk to your doctor before using non-drowsy cold medicines, or anti-fever meds (like Tylenol) while taking quinapril. These medicines may contain anti-histamines which can cause drowsiness, or decongestants which can increase blood pressure.

Quinapril can cause dizziness, light-headedness, or fainting. Do not sit or stand up quickly if you feel dizzy.

Quinapril may interfere with certain cardiac tests.

Sources & references used in this article:

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A pharmacodynamic and pharmacokinetic comparison of intravenous quinaprilat and oral quinapril by E Breslin, E Posvar, M Neub, D Trenk… – The Journal of …, 1996 – Wiley Online Library

Stabilization of quinapril using magnesium oxide by JE Daniel, MR Harris, GC Hokanson… – US Patent 6,417,196, 2002 – Google Patents

Quinapril and its metabolite quinaprilat in human milk by EJ Begg, RA Robson, SJ Gardiner… – British journal of …, 2001 – Wiley Online Library

Development and In Vitro Evaluation of Buccal Tablet of Quinapril Hydrochloride by AN Ranade, NS Ranpise, GS Sanap, RR Kulkarni – Ind J Pharm Edu Res, 2011 – ijper.org

Simultaneous determination of quinapril and its active metabolite quinaprilat in human plasma using high-performance liquid chromatography with ultraviolet … by C Abbara, G Aymard, S Hinh, B Diquet – Journal of Chromatography B, 2002 – Elsevier

Pharmacokinetics of quinapril in patients with renal dysfunction by K Onoyama, H Hirakata, S Okuda, T Sakemi… – Current therapeutic …, 1993 – Elsevier

Pharmacokinetics and bioequivalence study of the two 20-mg quinapril hydrochloride tablet formulations in healthy Thai male volunteers by N Rojanasthien, N Nasangiam, B Kumsorn… – Medical journal of the …, 2008 – thaiscience.info