Onycholysis Hyperthyroidism (OH) is a rare condition which occurs when the body’s immune system attacks its own tissues. This results in the destruction of healthy tissue. It is caused by overstimulation of certain cells in the thyroid gland causing them to produce too much hormones, resulting in symptoms such as weight gain, fatigue, depression and irritability.
The cause of ONYCHOLYSIS HYPERTYROIDISM is unknown. There are several theories as to what causes it, but no one knows for sure. Some believe that there may be genetic factors involved, while others say that environmental factors play a role.
The most common theory is that it develops from exposure to iodine during pregnancy or childhood.
In some cases, ONYCHOLYSIS HYPERTENSION can develop after a person consumes large amounts of fish or seafood. These foods contain high levels of iodine. Other times, ingestion of contaminated water can result in ONYCHOLYSIS HYPERTENSION.
Symptoms include weight loss, fatigue and depression.
There are two types of ONYCHOLYSIS: primary and secondary. ONYCHOLYSIS PRIMARY is a condition that exists all by itself. It is not caused by any other disorder.
ONYCHOLYSIS SECONDARY occurs as a result of other medical conditions, such as:
THYROID DISEASE: ONYCHOLYSIS and HYPERTHYROIDISM are closely related. In fact, many people who have hyperthyroidism also have ONYCHOLYSIS of their fingernails and toenails.
REJUVINATION: Many people begin to experience ONYCHOLYSIS after they reach middle age. Changes in hormone levels, stress, illness, and other factors can cause this condition in people over 40.
SOLVING ONYCHOLYSIS requires treatment for the underlying disorder. Onycholysis is a common symptom of hyperthyroidism, and treatment for this condition involves the use of antithyroid drugs to control the level of thyroid hormones in the blood.
Various other treatments may be used, depending on the cause of onycholysis. For example, people who develop onycholysis from taking certain medications may need to switch to a different drug. People with thyroid disorders may need to have their condition treated with medication.
In some cases, onycholysis can be effectively treated with simple lifestyle changes.
To help prevent the condition from occurring, you should always wear protective gloves when doing household chores and working in your garden. Also, avoid wetting your hands and feet for extended periods of time. When you wash your hands, ensure that you don’t leave them under running water for more than a few seconds.
If you have a cut or abrasion, make sure you keep it dry by wrapping it with a bandage.
Also known as onychia, onychomycosis is a fungal infection of the toenails and fingernails. It is the most common type of nail disease. Fungi can attack any one of the nails but are mostly found in the toenails.
People with diabetes are at greater risk of getting onychomycosis. The infection can also occur in people with other medical problems such as HIV, cancer, and a disorder that affects the immune system called AIDS.
It is very important to treat this infection because it can lead to serious problems with your nails, including making them discolored or even causing them to fall off. In some cases, the fungus can spread and infect other parts of the body.
This condition is also known as tinea unguium.
A type of fungal infection, onychomycosis affects the toenails and fingernails. It is the most common nail disease, affecting up to 10% of people at some point in their lives. Elderly individuals are most commonly affected.
There are two types of onychomycosis: non-infective and infective.
Non-infective onychomycosis (also known as dystrophic onychomycosis) is not caused by an infection from a fungus but may appear similar to infective onychomycosis. In this condition, an alteration or injury to the nail causes thinning of the nail and a discoloration. This change may occur as a result of an injury or may be caused by some diseases such as leprosy, psoriasis, eczema, or some types of thyroid disorders.
Some drugs may also cause this condition.
Infective onychomycosis (also known as malignant onychomycosis) is caused by an infection of a nail by any one of several species of fungi that are usually found on the skin or in the air. An injury or some condition that causes a break in the skin may allow the fungus to infect the nail. The most common fungi implicated are those of the genus Trichophyton (Trichophyton rubrum, T.
mentagrophytes, T. verrucosum, and T. violaceum).
Infective onychomycosis is further classified as being either non-melanotic or melanotic.
Non-melanotic onychomycosis is the most common form of fungal nail infection and is the form most often seen in patients with a history of diabetes. The infection rarely causes any symptoms and is identified by white or gray areas under the nail. As the infection progresses, the entire nail may become brittle and begin to break into small pieces.
This type of fungal nail infection does not usually affect normal skin.
Melanotic onychomycosis is a rarer form of infection that produces black spots under the nail. The spots appear where the fungus has grown deeply into the nail bed, interfering with blood supply to that area. This type of fungal nail infection may also cause abnormal skin sensations or changes in skin pigmentation.
These symptoms are similar to those caused by some types of skin cancer and a skin biopsy may be necessary to make a specific diagnosis.
Some fungi produce flakes or scales on the nail that may be confused with nail psoriasis.
Sources & references used in this article:
Onycholysis: an overview. by CR Daniel 3rd – Seminars in Dermatology, 1991 – europepmc.org
Photosensitivity and photo-onycholysis due to demethylchlortetracycline by N ORENTREICH, LC HARBER… – Archives of …, 1961 – jamanetwork.com
Chronic paronychia and onycholysis: a thirteen-year experience. by CR Daniel 3rd, MP Daniel, CM Daniel, S Sullivan… – Cutis, 1996 – ncbi.nlm.nih.gov
Onycholysis in hyperthyroidism by MN Luria, SP ASPER JR – Annals of internal medicine, 1958 – acpjournals.org
Onycholysis: a classification and study by LF Ray – Archives of dermatology, 1963 – jamanetwork.com
Primary onycholysis of the big toenails: a review of 113 cases by R Baran, G Badillet – British Journal of Dermatology, 1982 – Wiley Online Library
Photo-onycholysis due to tetracycline hydrochloride and doxycycline by SB Frank, HJ Cohen, W Minkin – Archives of Dermatology, 1971 – jamanetwork.com
Drug-induced photo-onycholysis: three subtypes identified in a study of 15 cases by R Baran, L Juhlin – Journal of the American Academy of Dermatology, 1987 – jaad.org
Multicenter study of a frozen glove to prevent docetaxel-induced onycholysis and cutaneous toxicity of the hand by F Scotté, JM Tourani, E Banu… – Journal of clinical …, 2005 – velo-medizinprodukte.com