Nortriptyline, Oral Capsule

Nortriptyline Side Effects: What are they?

The most common side effect of nortriptyline is drowsiness. Other possible side effects include dizziness, headache, nausea, vomiting, anxiety, agitation or depression. These are some of the potential adverse reactions associated with the use of nortriptyline. They may occur at any time during treatment and usually resolve themselves within a few days without medical attention.

If these symptoms persist or worsen, consult your doctor immediately.

How Do You Know If You Have Taken Too Much?

You will not experience all of the following negative side effects if you take too much of nortriptyline. However, you may experience one or more of them. Keep in mind that many people do not have any negative reaction to taking too much of this drug. In fact, it is often used as a first line medication when other treatments fail.



Nausea and Vomiting (May Cause Diarrhea)

What Are Some Commonly Used Dosage Levels For Nortriptyline? How Is It Determined?

There are two commonly used dosages levels for nortriptyline. One is the maximum recommended dose level which is 50 mg per day. The second is the lowest effective dose level which is 1/2 of this amount. The dosages are usually increased gradually until a therapeutic effect is achieved or side effects appear.

What Kind Of Interactions Should You Be Concerned About?

There are several medications that must not be taken with Nortriptyline due to the risk of serious health consequences. These include Zantac, Prozac, and Trileptal among others. Before taking this drug you should consult your doctor if you are currently undergoing any type of treatment for mood or behavior problems.

Always let your doctor know about all the prescription and over the counter drugs, vitamins, or herbal supplements that you are taking.

Do You Experience Withdrawal Symptoms When You Stop Taking It?

Withdrawal symptoms are common with many types of drugs. Nortriptyline is no exception. There are several types of these symptoms that you might experience, including:





Insomnia (Poor Quality Sleep)

Nausea and Vomiting

These symptoms are usually very minor and resolve themselves after a few days. In some cases, patients may need to take an anti-depressant such as nortriptyline again to relieve them.

These symptoms can also be treated with other medications, typically benzodiazepines.

How Long Does It Stay In Your System?

Nortriptyline is quickly eliminated from the human body. The half-life, or the amount of time it takes for the drug to be reduced by one half in the body, is usually quite short at only 7 to 9 hours.

What Happens If You Overdose?

A majority of the time, overdoses of this medication are not fatal and only cause mild to moderate negative side effects. Some of these include excessive drowsiness, vomiting, and coma in rare cases. Elderly patients are more susceptible to these types of reactions if they overdose.

If you do overdose on this medication you should seek immediate medical attention.

What Should You Do In Case Of An Overdose?

In case of overdose, you should seek immediate medical attention. The drug will most likely be eliminated from your body before any serious symptoms begin to show. If they do, then the medical professionals will treat the symptoms in the same manner as they would if you were using other types of antidepressant medication.

Where Can You Find Nortriptyline?

This medication is usually sold under the brand name of Aventyl and Pamelor. It is most commonly available as 25 mg, 50 mg, or 75 mg tablets. The drug can be purchased at most pharmacies without a prescription though it may require one in some states and countries.

What Is The Legal Status Of This Drug?

In the United States, this drug is a prescription medication and is only available for patients with depression. Laws concerning these types of drugs differ from country to country so it is advised that you check your local laws if you want to use it for another reason.

What Is The Recommended Dosage?

The usual dosage level is between 50 to 100 mg per day.

Sources & references used in this article:

First pass hydroxylation of nortriptyline: concentrations of parent drug and major metabolites in plasma by G Alvan, O Borgå, M Lind, L Palmer… – European Journal of …, 1977 – Springer

Effect of nortriptyline on symptoms of idiopathic gastroparesis: the NORIG randomized clinical trial by HP Parkman, ML Van Natta, TL Abell, RW McCallum… – Jama, 2013 –

Toxicology of nortriptyline hydrochloride by DB Meyers, RM Small, RC Anderson – Toxicology and applied …, 1966 – Elsevier

Pharmacokinetics of intravenous and oral amitriptyline and its active metabolite nortriptyline in Greyhound dogs by C Norkus, D Rankin, B KuKanich – Veterinary anaesthesia and analgesia, 2015 – Elsevier

The availability of orally administered nortriptyline by B Alexanderson, O Borgå, G Alvan – European Journal of Clinical …, 1973 – Springer

A sequential trial comparing two plasma levels of nortriptyline by G Burrows, LR Turecek, B Davies… – Australian and New …, 1974 – Taylor & Francis