What are Lipotropins?
Lipotropin is a term used to refer to two different drugs: Liraglutide (a synthetic version of the natural lipid) and Liraglutide acetate (an analog of the natural lipid). Both drugs have been shown to improve cholesterol levels in humans. However, they differ in their mechanism of action. The drug with higher affinity for LDL receptors increases HDL levels while lowering triglycerides and increasing good cholesterol.
The drug with lower affinity for LDL receptors increases triglycerides and lowers HDL levels.
How do Lipotropins Work?
In the human body, there are two types of fat cells: white and brown. White adipose tissue is stored primarily in your abdomen, but it’s also present in other parts of your body such as your hands, feet, neck and face. Brown adipose tissue is stored mainly in your legs, arms and back. When you exercise, your muscles burn up white fat cells which releases heat energy into your bloodstream. Your liver then converts some of this heat energy into glucose and uses it to maintain blood sugar levels.
However, when you eat too much carbohydrate or too many calories from protein, fats or alcohol, your body starts burning up brown fat cells which release heat energy directly into the bloodstream instead of using the stored glucose as fuel. This is why some people store excess fat around the torso or belly instead of the limbs.
Liraglutide and Liraglutide Acetate both encourage your body to burn off excess white fat by increasing the number of brown fat cells in the body. They do this by increasing the number of receptors for iralglatide (a natural hormone that triggers thermogenesis or heat production) in the body. In addition, they also decrease the number of receptors for glucagon which is a hormone that triggers fat storage in the body.
What does this mean for you?
Most people store excess fat around the belly (visceral fat) or the liver (hepatic fat). This is especially true for those with type 2 diabetes. Having too much visceral or hepatic fat can cause serious health problems. In some cases, it can even lead to fatal conditions. However, the right combination of lipotropins can help your body burn off excess fat. It can also decrease the onset of type 2 diabetes and increase the number of good cholesterol (high-density lipoprotein or HDL).
However, it’s important to note that lipotropins are only safe for healthy adults over the age of 18. Those who are pregnant, breastfeeding or have a history of heart disease should not take this medication.
Lipotropins and Glucagon
Lipotropins are also known as glucagon-like peptide 1 (GLP-1) agonists. These drugs work in a similar manner to the natural human hormone, glucagon. They make your body release excess insulin into the system, improve how sensitive your body is to the insulin you produce and help burn off excess fat.
Lipotropins also bind to a group of cells in your pancreas called L cells. They are responsible for producing and releasing the natural human hormone, glucagon. When lipotropins bind to these cells, they trigger an increase in the amount of glucagon that gets released into the bloodstream.
In turn, this helps your body break down excess blood sugar and burn off fat.
What are lipotropins used for?
There are several different lipotropins available. These drugs are primarily used to help people with type 2 diabetes or prediabetes increase their sensitivity to insulin and lose weight. They can be used alone or in combination with other medications to help people with type 2 diabetes reduce the amount of sugar in their blood.
In addition, these drugs are used in the treatment of obesity, dyslipidemia (elevated LDL cholesterol or “bad” cholesterol and reduced HDL cholesterol or “good” cholesterol), HIV lipodystrophy and various types of hepatitis.
At this time, there are several different drugs that fall under the lipotropin category. The most common include:
EXENATIDE (Byetta)
This drug is used to improve blood sugar control in adults with type 2 diabetes. It works by slowing the breakdown of sugars and carbohydrate in your body while also making your body more sensitive to insulin.
The FDA approved this drug for use in 2007. It is currently available in a single dose injection or an auto-injector, which you can give to yourself. Common side effects may include: nausea, diarrhea, headache, vomiting, dizziness and sleep problems.
DINITROTUBERIC ACID (Pitressin)
This drug is used to help increase the breakdown of fat in your body. It also helps break down excess sugar and carbohydrate in your body.
Sources & references used in this article:
Ipamorelin–What Is It & How Does It Work? Benefits, Side Effects & Dosage Overview by N Bausek – fitnessedge.net
Effect of lipotropic vitamins on the alkali reserve of the blood plasma. by R Lecoq – Compte rendu des seances de la Societe de biologie, 1948 – cabdirect.org
Effect of lipotropic substances on the enzymes of the liver made fatty by carbon tetrachloride. by A Bergamini, A Bendandi, G Maggi… – Bollettino della Societa …, 1955 – cabdirect.org
The effects of lipotropic substances on phospholipide synthesis in patients with and without chronic hepatitis as measured by radioactive phosphorus. by D Cayer, WL Cornatzer – Southern medical journal, 1949 – cabdirect.org
Antagonism of vitamin B12 and cortisol relative to lipotropic and immunological properties. by C Hadnagy, F Gyergyay – Internationale Zeitschrift fur …, 1967 – cabdirect.org
Boston Testosterone Partners by DD Federman, GA Walford – Men’s Health, 2012 – bostontestosterone.wordpress.com
Mechanism of action of lipotropic substances from the pancreas: behaviour of oxygen consumption of fatty liver from the rat. by L Arrigo – Quad Nutrizione, 1954 – cabdirect.org
Monthly Archives: July 2012 by S Conard – b12.kentuckyclassifieds.net
