Does Tonalin Have Side Effects

Does Tonalin Have Side Effects?

The following is a brief overview of the main concerns surrounding the use of tianeptine (Dosage: 1-2 mg/kg) and its potential side effects. The reader should keep in mind that these are only some of the possible side effects that could occur with this drug. Some may not occur or they may be milder than others. There have been no clinical trials on any adverse reactions associated with using this medication.

Tianeptine is a selective serotonin reuptake inhibitor (SSRI). SSRIs work by increasing levels of the neurotransmitter serotonin in your brain.

They are commonly used to treat depression, anxiety disorders, obsessive compulsive disorder (OCD), and other mental illnesses. The most common side effect of SSRIs is decreased appetite and weight loss. Other possible side effects include dizziness, nausea, insomnia, headache, dry mouth and constipation. These side effects usually go away within a few days of stopping the medication.

In addition to the side effects listed above, there have been reports of tianeptine causing abnormal heart rhythms and even death in certain individuals. Although these reports are rare, they do exist and if you experience one or more of them, stop taking this medication immediately and consult your doctor.

There are also concerns that it could cause serious harm to a developing fetus. This drug should not be used if you are pregnant or planning on becoming pregnant.

It is also recommended that women who are nursing consult their doctor before taking this medication.

If this medication is taken in combination with other drugs, side effects can be enhanced and in some cases life-threatening. These include alcohol, stimulants such as cocaine and amphetamines, certain pain killers, and most psychiatric medications.

If you are taking any prescription or over-the-counter medication, be sure to consult your doctor or pharmacist before taking this drug.

If you notice any concerning symptoms, stop taking the medication and seek immediate medical attention. These could include severe nausea, vomiting, and seizures.

If you experience signs of an allergic reaction such as itching, hives, swelling or trouble breathing, seek immediate medical attention.

Lastly, as with any medicine, there is always the potential for abuse or dependence. This medication has no known potential for dependence or abuse.

There is a small possibility that you may experience a headache, upset stomach, or nausea after taking tianeptine. If this occurs, take an over-the-counter pain reliever such as ibuprofen or acetaminophen and the symptoms should subside.

What is tianeptine?

Tianeptine is a chemical that is made from roots of the trough flower plant. It is used to treat depression, anxiety, and other mood problems. It may also be used to help you sleep or to reduce irritability caused by mental illness or alcohol withdrawal.

Tianeptine is also known as Stablon®, Coaxil®, and Tatinol®.

Does tianeptine work for everyone?

Everyone reacts differently to tianeptine, so it is difficult to predict who will benefit from this drug. In most cases, you should begin to feel its effects with 7 to 10 days of use. If you do not experience any benefits within one month of use, it is unlikely that this drug will help you.

You should consult your doctor if you feel tianeptine is not working for you after a 4 week period or if your condition suddenly worsens.

How do you use tianeptine?

The recommended initial dose of tianeptine is 12.5mg once a day, taken with a glass of water. Never take more than 25mg in a single dose. Do not take more than 50mg a day.

To prevent sleep problems, take the last dose no later than 6:00 PM.

Tianeptine can be taken with or without food. It may take time for your body to adjust to the medication.

Do not suddenly stop taking this medication. Always follow your doctor’s instructions.

Store this medication at room temperature and keep it away from moisture, heat, and light.

What are the potential side effects of tianeptine?

The most common side effects of tianeptine include:



upset stomach


abdominal pain

Less common side effects (occurring in less than 1% of people) include:

altered sense of taste or smell

vertigo (spinning sensation)

blurry vision

Less common but more serious side effects (occurring in less than 0.1% of people) include:

changes in behavior, agitation, or confusion



rash or hives (itchy bumps on the skin)

muscle weakness or aching

Stop taking this medication and get emergency medical help if you have any of these symptoms:

chest pain or an irregular heartbeat

Stop taking this medication and call your doctor immediately if you notice any signs of liver problems (such as nausea, vomiting, loss of appetite, tiredness, right upper abdominal pain, or dark urine).

Because tianeptine can be habit-forming, you should never share this medication with another person.

How can tianeptine affect your ability to drive or operate machinery?

Do not drive or operate machinery until you know how this medication will affect you. This medicine may cause dizziness or blurred vision.

Sources & references used in this article:

Scientific Opinion on the safety of “conjugated linoleic acid (CLA)‐rich oil”(Tonalin® TG 80) as a Novel Food ingredient by EFSA Panel on Dietetic Products, Nutrition and … – EFSA …, 2010 – Wiley Online Library

… substantiation of a health claim related to an equimolar mixture of the CLA isomers c9,t11 and t10,c12 (marketed as Clarinol® and Tonalin®) and “contributes to a … by European Food Safety Authority … – EFSA Supporting …, 2015 – Wiley Online Library


Clinical trial results support a preference for using CLA preparations enriched with two isomers rather than four isomers in human studies by JM Gaullier, G Berven, H Blankson, O Gudmundsen – Lipids, 2002 – Springer

Cis-9, trans-11 and trans-10, cis-12 CLA mixture does not change body composition, induces insulin resistance and increases serum HDL cholesterol level in rats by M Haugen, R Vikse, J Alexander – Norw Institute Public Health, 2003

Effects of conjugated linoleic acid supplementation during resistance training on body composition, bone density, strength, and selected hematological markers by …, CM Sabarense, JO do Amaral Corrêa… – Journal of oleo …, 2015 –