Complement Test

What is Complement Blood Test?

Complement blood test measures the amount of hemoglobin A1c (HbA1c) in your blood. HbA1c is a measure of how much sugar your body produces in your bloodstream. Your doctor will check the level of your blood sugar levels every six months to see if you need insulin or other treatment.

Your doctor will also check your blood sugar levels when you have diabetes. If the level of your blood sugar is too high, it may cause problems such as low energy, fatigue, weight gain and even seizures. When the level of your blood sugar is too low, it can lead to complications such as blindness or kidney failure.

The most common type of diabetes is Type 1 Diabetes which affects one out of every 10 men and women ages 15 to 44 years old. Type 2 Diabetes occurs when there is not enough insulin produced by your pancreas to control the level of glucose in your blood.

How Does Complement Test Work?

The results of the C4 and C5 tests are used together to determine whether you have prediabetes or diabetes. Prediabetes means that you do not produce enough insulin in your body to keep up with the amount of sugar in your blood. Your pancreas does not produce enough insulin, and as a result you need external insulin injections to control your blood sugar level.

Who Should Have Complement Blood Test?

If you are age 45 or older, you should have this test every three years. You should have this test performed more often if you are a man over age 60 or a woman over age 65. Your test may also be performed more often if you are overweight or have a family history of diabetes.

If you have any symptoms of high blood sugar, such as excessive urination, increased thirst, extreme hunger and fatigue, you should speak with your doctor about your concerns. He may recommend the test to help determine if you have blood sugar issues.

What Does a Normal Complement Blood Test Result Look Like?

A normal HbA1c level is less than 6.5 percent. A reading less than 5.7 indicates a low risk for developing diabetes, a reading between 5.7 and 6.4 indicates prediabetes, and a reading greater than or equal to 6.5 indicates diabetes.

If you are age 45 or older, your doctor will take the test again after two or three years to see if your HbA1c level has changed. If your level has increased from one test to the next, or if it has gone up significantly from your initial test, you are at an increased risk of developing diabetes.

What Does a Complement Blood Test Result Indicating Diabetes Look Like?

A person with high blood sugar levels will have an HbA1c reading of 6.5 percent or higher.

What Does a Complement Blood Test Result Indicating Prediabetes Look Like?

A reading between 5.7 and 6.4 percent indicates prediabetes. If left untreated, you are at risk of developing diabetes within 10 years.

What Are the Complications of Having a Complement Blood Test?

There are no complications from having a complement blood test.

What Else Should I Know?

If you or a family member has been diagnosed with type 1 or type 2 diabetes, it is important to maintain proper control over your disease by following your doctor’s advice. The longer you have the disease, the more likely you are to have complications such as heart and kidney disease, vision problems and nerve damage.

If you have prediabetes, making lifestyle changes such as exercising on a regular basis and following a diet recommended by your doctor can help prevent the onset of diabetes. You should also monitor your blood sugar levels at home to make sure they are staying within a normal range.

Sources & references used in this article:

A complement-fixation test for measuring Australia antigen and antibody by RH Purcell, PV Holland, JH Walsh, DC Wong… – The Journal of Infectious …, 1969 – JSTOR

The complement fixation test in the diagnosis of virus infections of the central nervous system by J Casals, R Palacios – The Journal of experimental medicine, 1941 – rupress.org

Rubella complement fixation test by JL Sever, RJ Huebner, GA Castellano, PS Sarma… – …, 1965 – science.sciencemag.org

Reiter protein complement fixation test for syphilis by GR Cannefax, W Garson – Public Health Reports, 1957 – ncbi.nlm.nih.gov

Evaluation of 12 commercial tests and the complement fixation test for Mycoplasma pneumoniae-specific immunoglobulin G (IgG) and IgM antibodies, with PCR used … by MFC Beersma, K Dirven, AP van Dam… – Journal of Clinical …, 2005 – Am Soc Microbiol

Immunological reactions of the Coxsackie viruses: II. The complement fixation test by LM Kraft, JL Melnick – The Journal of experimental medicine, 1950 – ncbi.nlm.nih.gov

Does peripheral knowledge complement control? An empirical test in technology outsourcing alliances by A Tiwana, M Keil – Strategic Management Journal, 2007 – Wiley Online Library