What Is Low-Grade Squamous Intraepithelial Lesion (LSIL)

What Is Low-Grade Squamous Intraepithelial Lesion (LSIL) ?

Low grade squamous intraepithelial lesions are benign growths of abnormal cells found throughout the body. They are usually small, less than 0.5 cm in diameter and have no obvious symptoms or signs. However, they may cause discomfort when touched or rubbed due to their rough texture.

These lesions do not spread easily from one part of the body to another. They are usually harmless and don’t require any medical attention. Some doctors believe that these lesions may be related to certain types of cancer.

These lesions are sometimes called “low grade” because they aren’t considered life threatening but they could still lead to pain if touched or rubbed too much.

The term “squamous cell carcinoma” refers to a group of cancers that are caused by squamous cell skin tumors. These include: basal cell carcinoma, invasive ductal carcinoma in situ (IDCSI), non-small cell lung cancer (NSCLC), non-Hodgkin lymphoma (NHL) and multiple myeloma.

Squamous cell carcinomas are the third most common types of cancer in the world. It’s usually diagnosed in older people; the average age of diagnosis is about 70 years. It can also occur in young adults.

They are less likely to be diagnosed at a younger age because they tend to show no obvious signs or symptoms during their youth. These lesions are generally slow growing and don’t spread quickly from one part of the body to another.

Sources & references used in this article:

… correlation with atypical squamous cells of undetermined significance (ASCUS) and low‐grade squamous intraepithelial lesion (LSIL) cytology diagnoses: An … by KA Dvorak, M Finnemore… – Diagnostic …, 1999 – Wiley Online Library

The significance of “low‐grade squamous intraepithelial lesion, cannot exclude high‐grade squamous intraepithelial lesion” as a distinct squamous abnormality … by TM Elsheikh, JL Kirkpatrick, HH Wu – Cancer Cytopathology, 2006 – Wiley Online Library

Prevalence of high grade squamous intraepithelial lesion (HSIL) and invasive cervical cancer in patients with low grade squamous intraepithelial lesion (LSIL) … by N Khuakoonratt, S Tangjitgamol… – Asian Pac J …, 2008 – pdfs.semanticscholar.org

… grade squamous intraepithelial lesion (LSIL) have low positivity rates when cotested for high‐risk human papillomavirus: Should we reconsider HPV triage for LSIL in … by MJ Thrall, DA Smith, DR Mody – Diagnostic cytopathology, 2010 – Wiley Online Library

“Low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion” is a distinct cytologic category: histologic outcomes and HPV … by CL Owens, DR Moats, FH Burroughs… – American journal of …, 2007 – academic.oup.com