Desoximetasone, Topical Cream
The drug Desoximetasone, Topical Cream (also known as Dutasteride) is used to treat male pattern baldness or androgenetic alopecia. This drug helps the hair follicles grow faster and prevents the hairs from falling out completely.
It works by blocking testosterone production in the body. The drug is available without a prescription only.
Dutasteride is approved by the FDA for treating benign prostatic hyperplasia (BPH). It’s effectiveness depends on how much DHT it contains.
According to some studies, the amount of DHT contained in topically applied doses of 5 mg/g or higher may prevent BPH from progressing into carcinoma in situ (CIS).
According to the Drug Enforcement Administration (DEA), there are no known contraindications for using Dutasteride. However, some patients have reported side effects such as acne, hirsutism, gynecomastia, and decreased libido.
These side effects usually disappear after stopping use of the medication.
Dutasteride is used for treating hair loss in men only. It is not intended for use by women and is not approved by the FDA for this purpose.
In addition, it should not be used in children or teenagers as there is no information available about its effects in these groups. It should also not be used by men with female sexual partners who are pregnant or could become pregnant. It may cause birth defects.
Before using the medication, you should tell your physician if you have liver or kidney disease, have an infection, or are allergic to any medications. You should also tell the physician if you are taking any other medications or over the counter products.
The drug may cause dizziness and drowsiness and be very dangerous to operate heavy machinery.
It’s not known exactly how this medication works to improve hair growth. However, it is thought to improve hair growth by increasing the size of hair follicles and decreasing the size of the scalp’s blood vessels.
How should I use dutasteride?
Desoximetasone is available only with your doctor’s prescription. Follow your doctor’s instructions if you use this medication.This medication is usually applied twice daily (in the morning and evening) to the areas of hair loss on the scalp. To help you remember to use dutasteride, apply it on the same days each week. Use enough medication to cover the affected area of the scalp. Massage the medication into the scalp until it is absorbed.
Desoximetasone is available as a cream or ointment for topical application on skin lesions. The usual dosage is twice daily (in the morning and evening) applied to the affected areas of skin.
What are the side effects of dutasteride?
Common side effects of dutasteride include: less interest in sexual activity (decreased libido), abnormal ejaculation, urinary problems, and swollen glands. Other side effects include: redness, scaling or itching of the treated skin area.
This is not a complete list of potential side effects. If you experience any discomfort not listed above, contact your doctor.
What if I forget to take a dose of dutasteride?
If you forget to apply your medication, apply it as soon as you remember. However, if it is almost time for your next application, skip the one you missed and return to your regular schedule. Do not apply double the amount.
Who should not take dutasteride?
You should not use dutasteride if you are allergic to any of its ingredients, or allergic to avodart or other 5 alpha-reductase inhibitors.
The FDA has also warned that dutasteride can cause fetal abnormalities if used during the pregnancy.
Do not use dutasteride without first talking to your doctor if you are a woman who can get pregnant and are either a teenager or have a sexually transmitted disease including chlamydia or gonorrhea.
Do not use dutasteride without first talking to your doctor if you are a man with a female sexual partner who is pregnant or could become pregnant.
Do not use dutasteride without first talking to your doctor if you are a woman with a male sexual partner who is taking dutasteride.
This medication may cause birth defects if the male fetus is exposed to it during pregnancy.
What if I have questions about dutasteride?
Ask your doctor about any concerns that you may have.
What other drugs will affect dutasteride?
Sources & references used in this article:
Randomized double-blind placebo-controlled trial in the treatment of alopecia areata with 0.25% desoximetasone cream by S Charuwichitratana, P Wattanakrai… – Archives of …, 2000 – jamanetwork.com
Desoximetasone–a new topical corticosteroid: short-and long-term experiences. by RC Savin – Cutis, 1978 – ncbi.nlm.nih.gov
Six‐month controlled study of effect of desoximetasone and betamethasone 17‐valerate on the pituitary‐adrenal axis by RC CORNELL, RB STOUGHTON – British Journal of …, 1981 – Wiley Online Library
Photosensitivity to desoximetasone emollient cream by MB Stierstorfer, RD Baughman – Archives of dermatology, 1988 – jamanetwork.com
A double blind trial of a new topical steroid formulation containing desoximetasone against fluocinolonacetonid cream. by E Lundell – Zeitschrift fur Hautkrankheiten, 1975 – europepmc.org
Cross-reactions to desoximetasone and mometasone furoate in a patient with multiple topical corticosteroid allergies by JCH Donovan, JG DeKoven – Dermatitis, 2006 – journals.lww.com
Florid Cushing’s syndrome and hirsutism induced by desoximetasone by T Himathongkam, P Dasanabhairochana… – JAMA, 1978 – jamanetwork.com
Activity of different desoximetasone preparations compared to other topical corticosteroids in the vasoconstriction assay by C Borelli, J Gassmueller, JW Fluhr… – Skin pharmacology and …, 2008 – karger.com